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Genomic studies by Pickart et al

were the first to encounter CHAC1 expression in the context of cancer cell death ( CHAC1 gene is highly upregulated in HNSC cancer after treatment with nisin which was then followed by cell death ( CHAC1 gene even though basal CHAC1 expression is significantly lower than in normal tissues (Lu et al., 2024)

And then couple that up also with some of the new information from neurons, because there are two papers to think in the last year that has highlighted neurons either in the hindbrain or a little bit further on