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In clinical trials, approximately 50% of participants achieved at least 15% body weight reduction, and roughly 30% achieved 20% or greater reduction at the highest doses

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Gastaldelli A., Stefan N., Hring H.U

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In a double-blind, placebo-controlled, phase 2b trial, patients with diabetes were administered all doses of tirzepatide, dulaglutide, or placebo

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If the liquid appears cloudy, has floating particles, or has changed color, it should be discarded immediately, even if it hasn't reached its expiration date