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Downward dose adjustments are less common but may occur if you experience recurrent hypoglycaemia (particularly if taking Mounjaro with insulin or sulfonylureas), significant weight loss beyond clinical targets, or persistent intolerable side effects

Slow titration and dose management can mitigate these effects

Gibellini L, Pinti M, Nasi M, De Biasi S, Roat E, Bertoncelli L, Cossarizza A (2010) Interfering with ROS metabolism in cancer cells: the potential role of quercetin