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This ATP-depleting futile 5-oxoproline cycle was first proposed by Kumar and Bachhawat to explain the development of Fanconi syndrome, ATP depletion, and 5-oxoprolinuria in children with nephropathic cystinosis (38,39)

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This is why doctors and trainers emphasize improving body composition rather than just crash dieting to hit a certain weight

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It may help prevent the muscle breakdown that occurs with exercise

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