It's a reminder that biology often operates through subtle interactions between seemingly simple components, creating emergent properties that exceed the sum of their parts
This prevents a vacuum or positive pressure from forming, making it easier and safer to handle
Also searched were the Agency for Healthcare Research and Quality evidence reports, Clinical Evidence, the Cochrane database, Essential Evidence, the Institute for Clinical Systems Improvement, the National Guideline Clearinghouse database, and the U.S
And its not because of any magic its because these are natural substances that our bodies make and are familiar with, so thats what gives them this incredible safety profile. The FDA, however, has publicly stated that there is not enough evidence from human clinical trials on the safety or efficacy of these drugs
Age and renal function are critical variables
This is because they have trouble absorbing B12 from food