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The formulation showed increased cytotoxicity after cell line experiments on B16F10 (mouse melanoma cells expressing the v3 integrin), but not on normal cells missing the HEK293 (integrin)

There was a significant decrease in PI3K/AKT expression, with a significant GSK-3 and TTBK1 overexpression in the hippocampus

doi: 10.1111/j.1463-1326.2010.01212.x

DebMandal M, Mandal S

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