Combining GHK-Cu with strong actives like high-strength retinoids or low-pH acids in the same routine can increase irritation
Patients who are already managing the once-weekly injection cadence of Semaglutide or Tirzepatide and do not want to add daily injections are not good candidates for GHK-Cu, not because of any contraindication, but because they wont maintain the protocol consistently enough to see results
The mechanisms are now well established, and the consistency of preclinical outcomes is why Ive personally continued to use GHK-Cu for years
Analgesics | Arthritis Foundation
Missing occasional applications is less concerning than sporadic, inconsistent use
This method allows for a slower, more controlled absorption, making it a preferred option for individuals seeking a gentle approach to boosting their glutathione levels over time