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The mechanism involves the modulation of the Wnt/beta-catenin pathway and growth factors (VEGF, bFGF) in the follicular microenvironment

One study covered in the review found that a topical containing Syn-Ake resulted in a 52% reduction in wrinkle size after 28 days of use.34 (As an interesting side note, you may have noticed that Syn-Ake kind of looks or sounds like the word snake. This is because the synthetic peptide Syn-Ake is an analog of a natural one called Waglerin-1, which is derived from the venom of the Southeast Asian temple viper.)34 As with Allies of Skin, much of the research behind the ingredients in The Ordinarys product is positive

Different brain regions, different pathways

The D-CuP is synthesized and then incorporated into a reactive oxygen species (ROS)-responsive hydrogel matrix to improve therapeutic compliance, culminating in the formulation of G/D-CuP

References Finkley M., Appa Y., Bhandarkar S

GHK-Cu in Weight Loss Protocols: The Clinical Truth GHK-Cu does not cause meaningful weight loss or appetite suppression in most patients