These results suggest that the angiopoietin 2-mediated astrocyte apoptosis induced by high glucose levels occurs through the v5-integrin/glycogen synthase kinase-3/-catenin signaling pathway
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Similar content being viewed by others Introduction According to JNC 7 (the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure), the relationship between blood pressure and cerebral-stroke risk is strong, continuous, graded, consistent, independent, predictive and etiologically significant
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Mechanism: Peptide therapy upregulates VEGF (vascular endothelial growth factor) promoting new blood vessel formation, modulates growth hormone receptor expression, enhances nitric oxide production supporting blood flow, and has anti-inflammatory effects through multiple pathways
doi: 10.1016/s1096-2867(97)80041-2