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Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism

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Placental ischemia/hypoxia is considered to play an important role through the induction of OS, which can lead to endothelial cell dysfunction [68, 180] and systemic vasoconstriction [184]

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Additionally, peptides that have been lyophilized must be kept at low temperatures in order to avoid degradation during the reconstitution process