Supplement & Nutritional Therapy Supplements to prevent muscle cramps with the best evidence include: Magnesium glycinate or citrate most effective for nocturnal leg cramps, toe cramps, and whole-body spasms related to electrolyte imbalance Potassium particularly valuable for leg cramps at night and charley horses in athletes Vitamin D3 + K2 addresses deficiency-related myofascial pain and muscle weakness Vitamin B12 important for nerve health
The Beneficiary Role of Selenium in Type II Diabetes: A Longitudinal Study
Mazini L, Rochette L, Admou B, Amal S, Malka G
Human StudiesWhat We Know Heres the catch: all of the research mentioned above has been done in animal models
Hormonal manipulation stimulates paracrine cells and promotes growth factors and other elements that saturate the treated areas with regenerative and healing benefits
This page notes that common side effects across nootropics can include headaches, nausea, insomnia, anxiety, and increased heart rate or blood pressure