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Pharmacologic options include short courses of anti-inflammatory drugs, neuropathic agents such as gabapentin or duloxetine when indicated, and topical agents for localized pain

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These medications mimic a natural hormone to regulate appetite and promote fat loss

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Whilst glucagon typically raises blood glucose, early Phase 2 trial data suggest that, when combined with GLP-1 receptor activation, its net effect may include increased calorie burning and a potential reduction in liver fat, without causing clinically significant rises in blood sugar