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Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS): Healthcare providers are strongly encouraged to complete a REMS compliant education program and to counsel patients and caregivers on serious risks, safe use, and the importance of reading the Medication Guide with each prescription [see WARNINGS]

Source Data underlying the figures are provided with this paper

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eprod Biol Endocrinol

Kim S-J, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CHS

Oxidative stress may contribute to the development of diarrhea with kidney-yang deficiency syndrome by inducing dysbiosis in the intestinal microbiota and damaging the intestinal epithelial barrier (Wang et al., 2016)