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Antioxid Redox Signal 10:15151526

[13] reported slightly higher serum GR activity in men compared to women, though the difference was not statistically significant

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Phosphorylation of ERs can occur with or without ligand binding 81 and ER transcription can be modulated by phosphorylation from intracellular kinases such as Akt and MAPKs 70 , increasing or decreasing ER -ERE affinity depending on the kinase and phosphorylation site 82

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