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The IGF protein family consists of signaling proteins (IGF-1, IGF-2), cell membrane receptor proteins (IGF-1R, IGF-2R) with tyrosine kinase activity and a series of IGF binding proteins (IGFBP1 - IGFBP6)
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Jan 22 2002;166(2):213-218
Persistent discomfort beyond this window is not typical and warrants a review of injection technique
However, persistent staining suggests a product quality issue
Mitochondrial abnormalities are another hallmark of cystinosis, with studies demonstrating reduced ATP production and evidence of metabolic imbalances [144, 146, 148]
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