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BOX 1 The immunobiology of MS The immune-mediated biology of MS identifies a prominent role of peripherally-derived T and B cells in acute active demyelinating lesions, with microglia, macrophages and astrocytes mainly responsible for chronic inflammation (Rodrguez Mura et al., 2022

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Most antioxidants are one-and-done

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Latest Clinical Trial Highlights (2026) Recent research continues evaluating: MOTS-c's role in type 2 diabetes reversal The effects of 5-Amino-1MQ on non-alcoholic fatty liver disease (NAFLD) Long-term NAD+ restoration in human adipose tissue Combination therapies pairing MOTS-c with exercise protocols Researchers continue monitoring ongoing trials before broader regulatory decisions are made

Hsieh, J