Safety Prior to injecting
(2016) Oral vitamin B12 replacement for the treatment of pernicious anemia
Serious side effects are rare when injections are administered correctly
These are typified by the following two enzymes: Methylmalonyl-CoA mutase [edit] Methylmalonyl coenzyme A mutase (MUT) is an isomerase enzyme that uses the AdoB 12 form and reaction type 1 to convert L-methylmalonyl-CoA to succinyl-CoA, an important step in the catabolic breakdown of some amino acids into succinyl-CoA, which then enters energy production via the citric acid cycle
That is a conversation to have with your GP or a specialist haematologist, not a reason to add a private injection on top of an NHS schedule without telling either provider
This is consistent with the methyl folate trap hypothesis (54), which predicts that, in vitamin B-12 deficiency, the inhibition of DNA synthesis and cell proliferation is removed upon administration of high doses of folic acid because of increased availability of nonmethylated folate