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Age-related cellular changes lead to NAD+ being increasingly consumed

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To induce the conditional expression of exon3-Ctnnb1 , nursing mothers of Nfatc1-CreER::Rosa-stop-tdTomato fl/wt ::Exon3-Ctnnb1 fl/wt pups and WT littermates were intraperitoneally injected with Tamoxifen doses totaling 40 g/g body weight for 8 days starting from E17.5

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