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Animal and cell studies show shifts in enzymes that convert cholesterol to sex steroids, suggesting possible effects on estrogen and testosterone levels

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oxidized) glutathione

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Hyperglycemia drives the accumulation of advanced glycation end products AGEs, which activate the RAGE/MAPK signaling axis, thereby inhibiting Col-II synthesis and promoting a catabolic state in chondrocytes (31)

A commenter noted that response rates to Federal surveys is declining as evidenced by reductions in response rates to Federal surveys in general and specifically the OAS CAHPS survey