Many factors contribute to these results, most notably where a patient starts, how long they stay on the medication, and how compliant they are with controlling external factors like activity/exercise and stress management/sleep
The protective effects of GLP-1 RAs against cardiovascular events have been demonstrated in several studies, thus supporting their application in patients with heart failure with preserved ejection fraction and DM2 ( Taken together, GLP-1 is a major metabolic and regulatory hormone, with many potential therapeutic implications beyond glycemic control, encompassing cardiovascular protection, enhanced renal function, and the potential benefits in hepatic disease
Recent developments in the evaluation and management of cardiorenal syndrome: a comprehensive review
As an NSAID, ibuprofen can affect the gastrointestinal tract, kidneys, and cardiovascular system, particularly with prolonged use or in individuals with pre-existing conditions
Diabetologia (1985) 28:13842
However, this approach carries higher risk of side effects and should only be considered under clinical guidance when tolerance at each dose has been clearly established
![M/36/5'6” [280lbs > 165lbs] (12 months) TRT, Ozempic and TRX : r/progresspics](https://i.redd.it/aupbomracqof1.jpeg)
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