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Energy intake has been reported to decrease by 1639% compared with similar patients not receiving GLP-1 RA treatment

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To further observe the transformation of peptides in living cells, we conjugated a fluorescent indicator Rhodamine B (RhoB) to peptides and synthesized RS and RC as analogs of NSBSO and NCBSO respectively (Additional file 1: Figs

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Higher levels are associated with deeper, more restorative sleep, while low levels contribute to shallow or fragmented rest