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However, in another intervention trial with combination therapy (53), the risk of adverse effects was significantly higher in the Se supplementation group, which we speculate may be related to unclear baseline Se levels in the subjects and a narrower safety window during Se treatment

Chuang YC, Chen SD, Jou SB, Lin TK, Chen SF, Chen NC et al

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For many in their 40s and 50s, the aggressive exfoliation of retinol can lead to "Inflammaging" a state of chronic irritation that can actually accelerate the breakdown of collagen

(1) Das bedeutet, dass unser Krper schneller altert