In some embodiments, Sodium Thiosulfate, Potassium Thiosulfate, HMTBa, Oltipraz, D-cysteine, D-methionine, or a combination thereof improves hair cell survival, function, viability, health, growth, or a combination thereof following chemotherapy-induced ototoxicity by at least or about 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or more than 95%
Tesofensine, a pharmaceutical compound under investigation for weight loss treatment, has shown promising results in clinical trials
The peptide appeared to lead to a significant attenuation of TBI-induced damage and improved early outcomes based on the observed experiments
Storage organization by form For unreconstituted (lyophilized) vials: Long-term supply (months out): freezer at -20C or below, in opaque container with desiccant Next vial to be reconstituted: can be moved to refrigerator a day or two before mixing Label each vial with the date received and the lot number if available For reconstituted vials: Always in the refrigerator at 2-8C Label with the reconstitution date and the planned discard date (30 days from mixing) Store in an opaque container or wrap in foil Keep away from the door and away from any food items with strong odors This organizational approach is the same system that works for managing tirzepatide vial lifespan and semaglutide vial shelf life
Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C
B.ArainH
