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It has been reported that hypnotics such as diazepam and zolpidem enhance GABAergic inhibitory signaling by prolonging the decay time constant of GABA A receptors in various brain region including thalamus, hippocampus, and neocortex [33,34,57-59]

While short-term use at moderate doses appears safe for most people, the effects of prolonged mega-dosing haven't been comprehensively studied

This chapter also examines how factors such as age, lifestyle habits (like diet, smoking, and environmental exposures), and genetic factors influence oxidative stress levels, increasing the risk of chronic diseases in specific populations

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Shen Y, Liu M, Botchway BOA, Zhang Y, Liu X