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Richardson et al

GLP-1 injectables must stay refrigerated between 36F and 46F until first use, then can remain at room temperature for up to 30 days

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As researchers tested GLP-1 drugs in these endometrial conditions, they discovered something unexpected

These include methionine (an essential amino acid involved in metabolism), inositol (a sugar alcohol involved in fat removal), and choline (an amine involved in the metabolism of fat)

This complete absence of immunogenic response indicates that the peptide structure is sufficiently similar to endogenous sequences that the immune system does not recognize it as foreign