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Likewise, infiltration of B cells into synovial tissue leads to autoantibody production against citrullinated peptides (ACPAs) and RF that can amplify the production of proinflammatory cytokines through synovial macrophages and subsequently the production of ROS [3,131]

Homogenates were 50 mg to 100 mg wet weight

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Arnold) containing a C-terminal HRV-3C protease cleavage site (3C-tag: LEVLFQGP) followed by a GSG linker and 8His tag

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