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Footprints of oxidative damage (downstream proxies) For downstream damage footprints, prioritize chemically specific assays: lipid peroxidation is best tracked by F 2 -isoprostanes and by MDA/HNE adductsnote that thiobarbituric acidbased colorimetry is prone to artifacts, so LC-MS/MS is preferred over simple spectrophotometric methods (Krl and Brzenicki 2023)
