Most information comes from patient forums and social media, where reports are mixed: some describe renewed appetite suppression on re-start, while others report weight gain during breaks and significant nausea on resuming previous doses, often requiring a full re-titration
A new concept in the treatment of Peyronies disease
start low and increase gradually
Banitalebi Dehkordi M, Madjd Z, Chaleshtori MH, Meshkani R, Nikfarjam L, Kajbafzadeh AM
However, years later in 2016, a pharmacological analysis of this ligand demonstrated interspecies differences between the rodent and human GIP system and also led to the conclusion that the human Pro3(GIP) was a potent partial agonist with the ability to activate the human GIP receptor with a maximal efficiency (E max ) of 90% compared to human GIP (68)
Acta (BBA)-Proteins Proteomics