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Retatrutide and the Future of Body Recomposition The retatrutide conversation is also part of a broader trend: patients want body recomposition, not just weight loss

As an Add-on to Metformin Monotherapy The reduction in HbA1c in T2DM patients on metformin monotherapy with SGLT2i + DPP4i FDCs is compared in Table 3

But buried in the data is a detail that matters more than most people realize: lean mass accounted for 26-40% of total weight lost in GLP-1 trials

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This disease spectrum ranges from isolated lipid deposition within hepatocytes through metabolic dysfunction-associated steatohepatitis (MASH), potentially advancing toward cirrhotic transformation, hepatic functional deterioration, and malignant hepatocellular transformation

Important distinction this is not the same thing as depression