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In a 2-year CV outcomes trial with semaglutide injection involving patients with type 2 diabetes mellitus and high CV risk, diabetic retinopathy complications (which was a 4-component adjudicated endpoint) occurred in patients treated with semaglutide injection (3%) compared to placebo (1.8%)

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This allows your appetite regulation to adjust gradually and may reduce the rapid weight rebound common with sudden cessation

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Some practitioners prescribe ondansetron (Zofran) for severe nausea that does not respond to dietary changes and the B6 in the compound