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Prior to any supplementation, all animals were subjected to the Morris water maze test to familiarize them with the task

Zhao Y, Ge Y, Zhang Z, et al

Through the inhibition of the TLR3 signaling pathway, it diminishes the uptake of oxidized lowdensity lipoprotein by macrophages, thereby effectively suppressing the formation of foam cells and the release of inflammatory cytokines

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This is not to say that all genetic associations in T1D are due to mutations in HLA genes as more than 40 additional T1D susceptibility loci have been identified that are not HLA genes