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Annatto-extracted tocotrienols improve glucose homeostasis and bone properties in high-fat diet-induced type 2 diabetic mice by decreasing the inflammatory response

However, the antioxidant effects of vitamin E depend on the nature of both oxidants and the substrates being oxidized

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This raises concern in patients undergoing sedated medical procedures such as EGD or colonoscopy

Consequently, a lipid-inflammation vicious cycle arises in the OA joint microenvironment