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doi: 10.1155/2011/279530 23 JallehRJMaratheCSRaynerCKJonesKLUmapathysivamMMWuTet al

Injection burden 1-2 injections per day on overlap days Best for Metabolic + mitochondrial pairing Cycle driver Retatrutide titration sets the pace Retatrutide Loading 1 2 4 6 9 mg (every 4 weeks) Frequency Once weekly Maintenance 9 mg or 12 mg weekly Route SubQ MOTS-c (intermittent - most common) Loading Start Week 5: 5 mg, 2x weekly Frequency 2-3x weekly Maintenance 5-10 mg, 2-3x weekly Route SubQ MOTS-c (low-dose daily - alternative) Loading Start Week 5: 200 mcg/day, +200 mcg every 2 weeks Frequency Daily Maintenance Up to 1 mg daily Route SubQ Weekly Schedule Example - Intermittent MOTS-c (Weeks 5-16) Monday Retatrutide 2 mg (morning) + MOTS-c 5 mg (pre-training) Tuesday Rest day Wednesday MOTS-c 5 mg (pre-training) Thursday Rest day Friday MOTS-c 5 mg (pre-training) Saturday Rest day Sunday Rest day Community protocols use different injection sites and separate syringes when both compounds are dosed the same day

9,764,003 was filed on June 21, 2013, and was granted on September 19, 2017

2021;54(3):e12993

Clinical application of GLP-1 in atherosclerosis There is substantial evidence that GLP-1 is involved in the function of the cardiovascular system [9]

2 Relationship between GLP-1 and obesity The mechanism for the decrease in GLP-1 secretion is incompletely understood in obese people