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ChuangHHPrescottEDKongHShieldsSJordtSEBasbaumAIet al

Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism

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A real-world study of nearly 1.8 million patients found that individuals with type 2 diabetes and obstructive sleep apnea (OSA) prescribed glucagon-like peptide-1 receptor agonists (GLP-1s) experienced greater survival benefits than those without OSA, suggesting that OSA status may enhance the mortality benefit of GLP-1 therapy