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B., & Napolitano, J

Its published record is unusually coherent for a research-stage peptide: a single medicinal-chemistry design paper, a short chain of combination clinical trials, and a set of recent structural studies together explain why the molecule exists in the form it does

On the enzymology of amino acid transport: transport in kidney and probably other tissues is mediated by a cycle of enzymic reactions involving glutathione

An endotoxin-free peptide helps ensure that observed effects are attributable to Cagrilintide itself rather than external contaminants

10.1038/s41569-018-0064-2 Nat Rev Cardiol