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Common side effects include injection-site redness, itching, swelling, joint stiffness, water retention, and tingling in hands or fingers

doi: 10.1038/tp.2014.4 PMCID: PMC3944636 Dr

FIC, which is broadly recognized as the natural animal equivalent of IC/PBS in humans, demonstrates similar pathological characteristics

It is longer-lasting, more stable and more effective than synthetic alternatives

It is reconstituted with bacteriostatic water or 0.9% acetic acid (the latter can improve stability in solution for some protocols)

Indoleacrylic acid produced by commensal Peptostreptococcus species suppresses inflammation