The compound was well tolerated with no evidence of genotoxicity, indicating its potential as a therapeutic agent for type 2 diabetes and obesity in humans
Treatment Schedule Examples
With heterogeneous evidence of the cardiovascular benefit, mortality, and potential risks of intensive glycemic control reported in several recent clinical trials, achieving good blood glucose control without increasing cardiovascular risk factors such as hypoglycemia and body weight gain is becoming more important [3,4,5,6,7]
Catalogue numbers for each primer assays are presented in (Supplementary Table 1)
This particularly applies to complex diseases, in which clinical manifestations result from intricate crosstalk among different molecular effectors [24]
Theranostics 6(12):2015 Sobu A, Machaliski B (2016) Trophic factors in the therapeutic challenge against ALS: current research directions