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For example, if a patient has recurrence of a previously resolved medical condition or if they gain more than 5% weight above their goal weight, then they are likely to continue to gain weight, says Lofton

Nausea is reported most, though people also experience the following side effects: Diarrhea Vomiting Constipation Abdominal pain Indigestion GLP-1 RAs often cause GI symptoms because the treatments slow the movement of food through your stomach

This approach helps scientists understand whether a drug target itself may influence disease risk