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Flavonoids are the major naturally occurring phenols (Evans, 2009)

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Signaling by hepatocyte growth factor in neurons is induced by pharmacological stimulation of synaptic activity

Theoretical risks of sustained angiogenic stimulation (promoting vascular supply to undetected pathological tissue) grow proportionally with the duration of use, as cumulative VEGF upregulation exceeds the controlled, injury-localized window intended by short-cycle research protocols

However, for most people with normal B12 levels, supplementation or injections do not significantly affect metabolism or fat loss

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