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Broader gene expression and signaling effects have been summarized in experimental models

Low glutathione may increase oxidative stress and reduce protection of mitochondria and cell membranes, potentially contributing to fatigue, poor concentration and reduced stress tolerance

DVT, which happens when a clot forms in a deep vein, can cause a life-threatening pulmonary embolism

Epidemiological studies showed that genes contribute to the vulnerability of multiple CNS disorders, such as major depressive disorders (MDD), schizophrenia and substance use disorders with heritability respectively of 3142%, 6480%, and 2379% [10,11,12,13]