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doi: 10.1016/j.bbi.2015.09.013

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In addition, mtDNA can interact indirectly with the mitochondrial antiviral-signaling protein (MAVS), which is anchored on the OMM and classically activated by viral RNA sensors such as RIG-I and MDA5 [133]

However, more research is needed to fully understand the time-dependent evolution of the alterations in mitochondrial dynamics markers in transgenic AD mice that exhibit classic AD pathologies, such as amyloid plaques and cellular degeneration

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