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therefore, these findings should not infer the absence of a doseresponse or duration effect

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Overexpression of miR-15a-3p increases ROS, intracellular Fe 2 , and malondialdehyde accumulation in CRC cells by binding to the 3UTR of GPX4 to suppress its expression [146]

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However, more water means a shorter usable window if you are drawing large volumes relative to the total solution