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doi: 10.1021/pr501254j

Wegovy remains one of the most effective licensed medical treatments for obesity when used as part of a broader plan

Further, unlike GLP-1, GIP increases triglyceride storage in white adipose tissue, does not delay gastric emptying, and may impact bone remodeling--functions that were thought to limit GIPs utility in T2D and weight loss

Semaglutide works by mimicking GLP-1, a hormone released in the intestine that aids in digestion and appetite suppression

On the other hand, researchers have claimed that given the cost of these drugs, if only 10% of overweight Medicare patients filled branded products, it would cost Medicare $26.8B a year

This is a game-changer, said UABs Timothy Garvey, M.D., co-author of the JAMA article and Butterworth Professor of Medicine in the Department of Nutrition Sciences