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Milliman estimates that a payer with high discontinuation rates may experience a 26% inefficiency in drug spend

Start with protein and soft carbs, keep portions small (about 46 ounces), and wait at least 3 hours before your next meal

Study populations, inclusion criteria, trial duration, comparator design, and development-stage context all limit how broadly findings can be interpreted

These processes help to control blood sugar levels, reduce food intake, promote weight loss, and improve overall metabolic health

Participant characteristics Across all trials, participants mean HbA 1c at baseline was 66.47 mmol/mol (8.2%), mean body weight was 91.5 kg and mean age was 58 years (Table 1)

Once-weekly semaglutide 72 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial