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Lifestyle commitment: Willingness to make dietary adjustments and increase physical activity while managing potential side effects alongside work and daily responsibilities

Zulewski H, Muller B, Exer P, et al

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49 These cell contents, also known as damage-associated molecular patterns (DAMPs), may bind to and activate Toll-like receptors in macrophages, promote the formation of inflammasome complexes, and induce the release of pro-inflammatory cytokines

In line with BSSM guidance and testosterone SmPCs (e.g., Nebido), TRT should be paused or the dose reviewed if haematocrit exceeds 0.54