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PMID 40789979

ICI monotherapy versus combined ICI is associated with fewer irAEs

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Numerous trials have consistently shown that GLP-1 RA and SGLT2i, individually, provide significant benefits for cardiovascular outcomes in participants with T2D and high cardiovascular risk and/or CKD

Clinical trials show tirzepatide produces 2022% average weight loss versus 1517% for semaglutide, but individual outcomes vary

Following general guidelines about brushing and flossing and visiting a dentist can help ward off these side effects, which generally resolve over time.