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Ten Key Takeaways for 2026 SGLT-2 inhibitor plus metformin is now first-line at least in the UK

Short-term use may provide clinical benefit for patients with specific metabolic goals, acute health markers requiring intervention, or as a bridge therapy

Do not try to "squeeze in" a dose before a surgical hold period

In PD models, oral administration of Curli-producing bacteria enhanced -syn aggregation and motor deficits in mice, whereas germ-free or antibiotic-treated mice had less -syn pathology [91, 92]

Introduction The postpartum period is a time of immense change

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