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Key Takeaways Modern travelers increasingly rely on specialized wellness solutions to combat fatigue

Acknowledgements This work was supported by National Key Research and Development Program of China (2021YFC2101500), the National Natural Science Foundation of China (31730004), and the General Program of Shanghai Natural Science Foundation (19ZR1413700)

Most marketed "drops" claim sublingual or buccal absorption, but there is little peer-reviewed evidence that offlabel compounded drops deliver consistent, therapeutic blood levels