10.1038/cddis.2014.267 147 WangW.ZhengY.WangM.YanM.JiangJ.LiZ
One of these classes (class I ferroptosis-inducing compounds, erastin derivatives) inhibits GPX4 through the depletion of glutathione, and the other (class II ferroptosis-inducing compounds, RSL3 derivatives) inhibits GPX4 directly, without glutathione depletion
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Only 9% of those on placebo reported similar results, showing the peptides meaningful effect
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The growth and carbon source consumption were followed over the cultivation time (Figure 6A)