Theoretical and community-reported concerns Broad tissue exposure ERR receptors are widely expressed across heart, brain, kidney, liver, adipose tissue, and gut, so systemic pan-ERR agonism is not tissue-selective
Ilkayeva, R.D
The review specifically noted that the fat transport mechanism makes carnitine most effective when combined with consistent exercise that provides the metabolic demand for fatty acid oxidation
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But GHK-Cus benefits arent limited to skin
Edge: SLU-PP-332 has the more direct cardiac dataset, in a disease model